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Two methods of cloning
Globe and Mail Update
Saturday, August 18, 2001

Embryo splitting, September 1999

  1. A fertilized egg is taken when the cell division has reached a total of eight cells.
  2. The cells are split into quadruplet embryos with two cells each. All four embryos, including their DNA, remain true to the original.
  3. Two quadruplet embryos are transferred into each surrogate mother. Both monkeys become pregnant with only one embryo.
  4. The first monkey miscarries.
  5. The second monkey gives birth to Tetra, a genetic copy of the original embryo.

Nuclear transfer technology, February, 1997

  1. DNA from a mammary cell is removed from an adult sheep.
  2. An unfertilized egg is removed from another sheep. Its nucleus, containing the DNA, is removed.
  3. The mammary cell DNA and unfertilized egg are fused.
  4. The egg develops into an embryo, which is transferred into a surrogate mother.
  5. The lamb contains DNA from the adult donor, but grows up to have slightly different characteristics.
Sources: Oregon Regional Primate Research Center and New York Times News Service

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